![]() It is designed to prevent cancer cells from multiplying inside the body. Keytruda (pembrolizumab) is a type of immunotherapy called a monoclonal antibody. For GE junction cancer, targeted therapy or immunotherapy, alone or with chemotherapy.įOR YOUR REFERENCE: What Medications Were Investigated in the KEYNOTE-590 Trial.Palliative laser surgery or electrocoagulation, esophageal stent, external or internal radiation therapy.Stage 4 cancer has spread to distant lymph nodes or organs.For GE junction cancer, chemotherapy plus immunotherapy (sometimes combined with targeted therapy for HER2-positive cancers). ![]() Chemoradiation or chemotherapy followed by surgery.For patients whose cancer has spread further in the esophagus or to nearby lymph nodes (stage 2) or through the esophagus wall and/or into nearby organs or tissues (stage 3), options include:. ![]() Patients with more advanced stage 1 cancer may receive chemoradiation before surgery and/or an immunotherapy drug after surgery. Stage 1 esophageal cancer has grown into the esophagus wall and is treated with surgery to remove the part of the esophagus that contains the cancer, sometimes followed by chemoradiation (chemotherapy and radiation therapy given at the same time).Treatment options for patients with GE junction cancer at various stages include the following 2,3: Adenocarcinomas that start at the GE junction also are treated as esophageal cancers. The two main types of esophageal cancer are squamous cell carcinoma, which most commonly starts in the neck and upper chest region, and adenocarcinomas, which start in gland cells (cells that make mucus) in the lower third of the esophagus. The lower part of the esophagus, where it connects to the stomach, is called the gastroesophageal (GE) junction. Esophageal cancer can start anywhere along the esophagus, which in adults is usually 11 to 13 inches long. Phase 4: occurs after FDA approval monitors safety and effectiveness in large, diverse populations and collects information on long-term side effects.įOR YOUR REFERENCE: What Is Gastroesophageal Junction Cancer?Ĭancer of the esophagus (or esophageal cancer) starts when cells in the lining of the esophagus begin to grow out of control. ![]()
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